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货号: STA00156
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: GRP78
应用: WB IHC
反应性 : Human Mouse Rat
宿主物种 : Rabbit
MW(Observed): 78kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500~1:2000 IHC 1:50~1:200
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : GRP78 BiP Antibody detects endogenous levels of total GRP78 BiP
别名 : GRP-78; GRP78; BIP; MIF2; HSPA5
数据库链接:
背景:
When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) (PubMed 8020977) pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER).


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