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货号: PL0986
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: DRP1
应用: WB,IF,ELISA
反应性 : Human,Mouse,Rat,Bovine
宿主物种 : Rabbit
MW(CalcμLated) : 82kD
MW(Observed): 82kD
同种型-Isotype : IgG,Kappa
偶联-Conjugate : Phospho
隐藏域元素占位
详细信息
修饰-Modification : Ser616
推荐稀释比 : WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT0754R
抗原&靶点信息
特异性 : Detects endogenous levels of DRP1 only when phosphorylated at Ser616(human,mouse), Ser637(Rat). The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):PAsPQ
基因名称 : DNM1L
蛋白名称 : Dynamin-1-like protein
别名 : DNM1L;DLP1;DRP1;Dynamin-1-like protein;Dnm1p/Vps1p-like protein;DVLP;Dynamin family member proline-rich carboxyl-terminal domain less;Dymple;Dynamin-like protein;Dynamin-like protein 4;Dynamin-like protein IV;HdynIV;Dynamin-rela
背景:
This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013],


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