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GSK3β Rabbit mAb

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说明书下载
货号: PL0974
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: GSK3β
应用: WB,IHC,IF,IP,ELISA
反应性 : Human,Mouse,Rat,Rabbit
宿主物种 : Rabbit
MW(CalcμLated) : 47kD
MW(Observed): 47kD
同种型-Isotype : IgG,Kappa
偶联-Conjugate : Unmodified

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT0816R

抗原&靶点信息

特异性 : Endogenous
基因名称 : GSK3B
蛋白名称 : Glycogen synthase kinase-3 beta
别名 : GSK3B;Glycogen synthase kinase-3 beta;GSK-3 beta;Serine/threonine-protein kinase GSK3B

数据库链接:

Organism

基因 ID

SwissProt

背景:

The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009],

细胞定位 : Cytoplasm . Nucleus . Cell membrane . The phosphorylated form shows localization to cytoplasm and cell membrane (PubMed:20937854). The MEMO1-RHOA-DIAPH1 signaling pathway controls localization of the phosphorylated form to the cell membrane (PubMed:20937854). .

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