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Histone H2A.X (Phospho Ser139) Rabbit mAb

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货号: PL1350
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Histone H2A.X Phospho Ser139
应用: WB,IHC,IF,IP,ELISA
反应性 : Human,Mouse,Rat,
宿主物种 : Rabbit
MW(CalcμLated) : 15kD
MW(Observed): 15kD
同种型-Isotype : IgG,Kappa
偶联-Conjugate : Phospho

隐藏域元素占位

详细信息

修饰-Modification : Ser139
推荐稀释比 : IHC 1:2000-1:8000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200,
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT0330R

抗原&靶点信息

特异性 : This antibody detects endogenous levels of Histone H2A.X only when phosphorylated at Ser139.This antibody does not recognize phosphorylated at other sites.
基因名称 : H2AFX
蛋白名称 : Histone H2A.x
别名 : H2AFX;H2AX;Histone H2A.x;H2a/x,γ-H2AX,

数据库链接:

Organism

基因 ID

SwissProt

背景:

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015],

细胞定位 : Nucleus

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