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货号: PG8659
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: SPHK1
应用: WB,ELISA
反应性 : Human,Rat,Mouse,
宿主物种 : Rabbit
MW(Observed): 42kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-2000;ELISA 1:5000-20000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : SPHK1 Polyclonal Antibody detects endogenous levels of protein.
基因名称 : SPHK1 SPHK SPK
蛋白名称 : Sphingosine kinase 1
别名 : Sphingosine kinase 1;SK 1;SPK 1;EC 2.7.1.91;
背景:
The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],


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