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货号: PD2168
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类：
靶点: CD314
应用： WB,ELISA
反应性 ： Human,Rat,Mouse,
宿主物种 ： Rabbit
MW(Observed)： 25kD
同种型-Isotype ： IgG
隐藏域元素占位
详细信息
推荐稀释比 ： WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成 ： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 ： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 ： -15°C to -25°C/1 year(Do not lower than -25°C
浓度 ： 1 mg/ml
克隆性 ： Polyclonal
抗原&靶点信息
特异性 ： CD314 Polyclonal Antibody detects endogenous levels of CD314 protein.
基因名称 ： KLRK1
蛋白名称 ： NKG2-D type II integral membrane protein
别名 ： KLRK1;D12S2489E;NKG2D;NKG2-D type II integral membrane protein;Killer cell lectin-like receptor subfamily K member 1;NK cell receptor D;NKG2-D-activating NK receptor;CD antigen CD314
背景：
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of
细胞定位 ： Cell membrane ; Single-pass type II membrane protein . Colocalized with HCST on the cell surface.
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