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TNF α Rabbit mAb

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货号: PL1241
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: TNFA
应用: WB,IHC,IF,IP,ELISA
反应性 : Human,Mouse,Rat,
宿主物种 : Rabbit
MW(CalcμLated) : 26kD
MW(Observed): 18kD
同种型-Isotype : IgG,Kappa
偶联-Conjugate : Unmodified

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:2000-1:10000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT0472R

抗原&靶点信息

特异性 : Endogenous
基因名称 : TNF TNFA TNFSF2
蛋白名称 : Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a)
别名 : TNF;TNFA;TNFSF2;Tumor necrosis factor;Cachectin;TNF-alpha;Tumor necrosis factor ligand superfamily member 2;TNF-a

数据库链接:

背景:

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008],

细胞定位 : Membrane

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