产品服务
信号通路
说明书下载
货号: PL1133
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: Chk1
应用: WB,IF,IP,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 54kD
MW(Observed): 54kD
同种型-Isotype : IgG,Kappa
偶联-Conjugate : Unmodified
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT0606R
抗原&靶点信息
特异性 : Endogenous
基因名称 : CHEK1
蛋白名称 : Serine/threonine-protein kinase Chk1
别名 : CHEK1;CHK1;Serine/threonine-protein kinase Chk1;CHK1 checkpoint homolog;Cell cycle checkpoint kinase;Checkpoint kinase-1
背景:
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2011],


微信客服