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货号: STA00067
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: HDAC2
应用: WB IHC ICC/IF IP FC
反应性 : Human Mouse Rat
宿主物种 : Rabbit
MW(Observed): 55kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:1000~1:2000 IHC 1:50~1:100 ICC/IF 1:50~1:100 IP 1:30 FC 1:50
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : HDAC2 Antibody detects endogenous levels of total HDAC2
别名 : HDAC2; HD2; Histone deacetylase 2; RPD3; YAF1; YY1 associated factor 1;
数据库链接:
背景:
In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA.


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