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货号: STA00922
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: KMT6
应用: WB IHC ICC/IF FC
反应性 : Human Mouse Rat
宿主物种 : Rabbit
MW(Observed): 98kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500~1:1000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : KMT6 / EZH2 Antibody detects endogenous levels of total KMT6 / EZH2
别名 : EZH 2; EZH1; EZH2; EZH2b; KMT 6; KMT6; KMT6A;
数据库链接:
背景:
Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.


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