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货号: STA00435
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: MLKL
应用: WB IHC
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 54kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500~1:2000 IHC 50~200
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : MLKL Antibody detects endogenous levels of total MLKL
别名 : Mixed lineage kinase domain-like protein; hMLKL;
数据库链接:
背景:
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.


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