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货号: STA00090
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: p21
应用: WB IHC ICC/IF IP
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 21kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : p21 Antibody detects endogenous levels of total p21
别名 : CAP20; CDKN1; CIP1; MDA-6; P21; SDI1; WAF1; P21cip1;
数据库链接:
背景:
The tumor suppressor protein p21 Waf1/Cip1 acts as an inhibitor of cell cycle progression. It functions in stoichiometric relationships forming heterotrimeric complexes with cyclins and cyclin-dependent kinases. In association with CDK2 complexes, it serves to inhibit kinase activity and block progression through G1/S. However, p21 may also enhance assembly and activity in complexes of CDK4 or CDK6 and cyclin D.


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