产品服务
信号通路
说明书下载
货号: STA00128
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: p53
应用: WB IHC ICC/IF IP
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 53kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : p53 Antibody detects endogenous levels of total p53
别名 : Cellular tumor antigen p53; Phosphoprotein p53; TP53; Tumor suppressor p53;
数据库链接:
背景:
Plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. It is postulated to bind as a tetramer to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor.


微信客服