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货号: STA00054
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: pro
应用: WB IHC ICC/IF IP FC
反应性 : Human Mouse
宿主物种 : Rabbit
MW(Observed): 35kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : pro Caspase 3 Antibody detects endogenous levels of total pro Caspase 3
别名 : CASP3; Caspase-3; APOPAIN; CPP32; CPP32B; SCA-1;
数据库链接:
背景:
Caspase-3 (CPP-32, Apoptain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins such as the nuclear enzyme poly(ADP-ribose) polymerase (PARP). Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires aspartic acid at the P1 position.


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