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货号: TPFL0325
货期: 现货
价格: 1350;2200;3000
所属分类:
靶点: MYD88
应用: WB, IHC, IF/ICC, IF-P, ELISA
反应性 : human, mouse, rat, pig, rabbit
宿主物种 : Mouse
MW(CalcμLated) : 33 kDa
MW(Observed): 33 kDa
同种型-Isotype : IgG2b
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
组成 : PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 : Protein A purification
储存 : Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 : 1000 ug/ml
克隆性 : Monoclonal
抗原&靶点信息
基因名称 : MYD88
蛋白名称 : myeloid differentiation primary response gene (88)
别名 : 2E10D3
背景:
MYD88 is a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. MYD88 is the key adaptor protein for the interleukin-1 receptor (IL-1R) and most Toll-like receptors (TLRs), which are essential for innate immunity and pathogen-associated molecular pattern recognition. Mutations in the MyD88 gene lead to the development of cancer in humans and mice suggesting that MyD88 also plays a cell autonomous role in tissue homeostasis.


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