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PD-L1/CD274 Monoclonal antibody

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说明书下载
货号: TPFL0319
货期: 现货
价格: 1350;2200;3000
+

所属分类:


靶点: PD-L1
应用: WB, IHC, IF/ICC, IF-P, ELISA
反应性 : human, mouse, rat, pig
宿主物种 : Mouse
MW(CalcμLated) : 290 aa, 33 kDa
MW(Observed): 45-50 kDa, 33 kDa
同种型-Isotype : IgG1
偶联-Conjugate : Unconjugated

隐藏域元素占位

详细信息

组成 : PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 : Protein G purification
储存 : Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 : 2000 ug/ml
克隆性 : Monoclonal

抗原&靶点信息

基因名称 : PD-L1
蛋白名称 : CD274 molecule
别名 : CD274, PD-L1, 2B11D11, B7 H1, B7-H1

数据库链接:

Organism

基因 ID

SwissProt

背景:

PD-L1, also known as CD274 or B7H1, stands for programmed cell death ligand 1. It is a type I transmembrane protein that is thought to repress immune responses by binding to its receptor (PD1), thus inhibiting T-cell activation, proliferation, and cytokine production. It contains V-like and C-like immunoglobulin domains. PD-L1 expression is regulated by various cytokines, such as TNF-α or LPS (ISSN: 1848-7718). Increased expression of this protein in certain types of cancers, e.g., renal cell carcinoma or colon cancer, correlates with poor prognosis.

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