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货号: TPFL0318
货期: 现货
价格: 1350;2200;3000
所属分类:
靶点: PGC1a
应用: WB, IF/ICC, ELISA
反应性 : human, mouse, rat, pig
宿主物种 : Mouse
MW(CalcμLated) : 91 kDa
MW(Observed): 70 kDa, 100 kDa
同种型-Isotype : IgG1
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
组成 : PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 : Protein G purification
储存 : Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 : 2000 ug/ml
克隆性 : Monoclonal
抗原&靶点信息
基因名称 : PGC1a
蛋白名称 : peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
别名 : PPARGC1A, 1C1B2, LEM6, Ligand effect modulator 6, PGC 1 alpha
背景:
PPARGC1A, also named as Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, is a 798 amino acid protein, which Contains 1 RRM (RNA recognition motif) domain and localizes in the nucleus. PPARGC1A is transcriptional coactivator for steroid receptors and nuclear receptors. PPARGC1A can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis and plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. PPARGC1A exists an isoform in the liver and the molecular weight of it is 77 kDa. Except for a deletion of 127 amino acids at the N terminus, the protein, termed L-PGC-1 α, is identical to PGC-1.


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