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货号: TPFL0316
货期: 现货
价格: 1350;2200;3000
所属分类:
靶点: PIK3CA
应用: WB, IHC, IF/ICC, FC , ELISA
反应性 : human, mouse, rat, pig, rabbit
宿主物种 : Mouse
MW(CalcμLated) : 1068 aa, 124 kDa
MW(Observed): 110 kDa
同种型-Isotype : IgG2b
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
组成 : PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 : Protein A purification
储存 : Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 : 1000 ug/ml
克隆性 : Monoclonal
抗原&靶点信息
基因名称 : PIK3CA
蛋白名称 : phosphoinositide-3-kinase, catalytic, alpha polypeptide
别名 : PI3K p110(alpha), PIK3CA, 1F6A7, EC:2.7.1.137, EC:2.7.11.1
背景:
PIK3CA belongs to the PI3/PI4-kinase family. It phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2. Defects in PIK3CA are associated with colorectal cancer (CRC). Defects in PIK3CA are associated with breast cancer. Defects in PIK3CA are associated with ovarian cancer. Defects in PIK3CA may underlie hepatocellular carcinoma (HCC). Defects in PIK3CA are a cause of keratosis seborrheic (KERSEB).


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