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Anti-DRP1/DNM1L Antibody

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说明书下载
货号: TPFL0265
货期: 现货
价格: 1280;2180;2800
+

所属分类:


靶点: DNM1L
应用: WB, IHC-P, IF/ICC, FCM, ELISA
反应性 : human, mouse, rat
宿主物种 : Rabbit
MW(CalcμLated) : 82 kDa
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated

隐藏域元素占位

详细信息

推荐稀释比 : Western blot (WB): 1:1000-8000; Immunohistochemistry (IHC): 1:50-400; Immunocytochemistry/Immunofluorescence (ICC/IF): 1:50-400; Flow Cytometry (Fixed): 1:50-200; Enzyme linked immunosorbent assay (ELISA): 1:100-1000
组成 : 500 ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.
纯化工艺 : Immunogen affinity purified.
储存 : 12 months from date of receipt,-20℃ as supplied.
浓度 : 500 ug/ml
克隆性 : Polyclonal

抗原&靶点信息

基因名称 : DNM1L
蛋白名称 : Dynamin-1-like protein
别名 : DLP1; DNM1L; DRP1

数据库链接:

Organism

基因 ID

SwissProt

背景:

Dynamin-1-like protein is a GTPase that regulates mitochondrial fission. In humans, dynamin-1-like protein, which is typically referred to as dynamin-related protein 1 (Drp1), is encoded by the DNM1L gene. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.

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