信号通路

联系我们

15392937510

地址:湖北省武汉市江夏区神墩四路 666 号武汉国英种业大厦A栋14F 
邮箱:pinuofei2017@163.com
TEL:15392937510

Anti-EPO Antibody

复制产品信息

说明书下载
货号: TPFL0264
货期: 现货
价格: 1280;2180;2800
+

所属分类:


靶点: EPO
应用: WB, ELISA
反应性 : human, mouse, rat
宿主物种 : Rabbit
MW(CalcμLated) : 21 kDa
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated

隐藏域元素占位

详细信息

推荐稀释比 : Western blot (WB): 1:500-2000; ELISA: 1:100-1000
组成 : 500 ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.
纯化工艺 : Immunogen affinity purified.
储存 : 12 months from date of receipt,-20℃ as supplied.
浓度 : 500 ug/ml
克隆性 : Polyclonal

抗原&靶点信息

基因名称 : EPO
别名 : EP; EPO; Epoetin; erythropoietin; MVCD2

数据库链接:

Organism

基因 ID

SwissProt

背景:

This EPO gene encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney, secreted into the blood plasma, and binds to the erythropoietin receptor to promote red blood cell production, or erythropoiesis, in the bone marrow. Expression of this gene is upregulated under hypoxic conditions, in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye, and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries, as well as antiapoptotic functions in several tissue types, and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies.

推荐产品

相关文献

留言咨询

留下您想咨询的信息,我们会尽快联系您

提交