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货号: TPFL0227
货期: 现货
价格: 1150;1870;2900
所属分类:
靶点: Carbonic Anhydrase 9 (CA9/G250)
应用: WB, IHC-P, IF/ICC, ELISA
反应性 : Human
宿主物种 : Rabbit
MW(CalcμLated) : 50 kDa
MW(Observed): Refer to figures
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500 - 1:2000 IHC-P 1:1000 - 1:4000 IF/ICC 1:50 - 1:200 ELISA Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
组成 : Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
纯化工艺 : Affinity purification
储存 : Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS containing 50% glycerol
克隆性 : Polyclonal
抗原&靶点信息
基因名称 : CA9
蛋白名称 : Carbonic anhydrase 9
别名 : MN; CAIX; Carbonic Anhydrase 9 (CA9/G250)
背景:
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.


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