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CD31 Polyclonal antibody

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说明书下载
货号: TPFL0220
货期: 现货
价格: 1350;2200;3000
+

所属分类:


靶点: CD31
应用: WB, IHC, IF-P, IF-Fro, ELISA
反应性 : mouse
宿主物种 : Rabbit
MW(CalcμLated) : 81 kDa
MW(Observed): 110-130 kDa
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated

隐藏域元素占位

详细信息

组成 : PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 : Antigen affinity purification
储存 : Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 : 650 ug/ml
克隆性 : Polyclonal

抗原&靶点信息

基因名称 : CD31
蛋白名称 : platelet/endothelial cell adhesion molecule 1
别名 : Pecam, PECAM 1, Pecam1, PECAM-1

数据库链接:

Organism

基因 ID

SwissProt

背景:

Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489).

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