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FNDC5 Polyclonal antibody

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说明书下载
货号: TPFL0195
货期: 现货
价格: 1350;2200;3000
+

所属分类:


靶点: FNDC5
应用: WB, IHC, ELISA
反应性 : human, mouse, rat
宿主物种 : Rabbit
MW(CalcμLated) : 212 aa, 24 kDa
MW(Observed): 25-30 kDa
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated

隐藏域元素占位

详细信息

组成 : PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 : Antigen affinity purification
储存 : Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 : 580 ug/ml
克隆性 : Polyclonal

抗原&靶点信息

基因名称 : FNDC5
蛋白名称 : fibronectin type III domain containing 5
别名 : Irisin, Fibronectin type III domain-containing protein 5, Fibronectin type III repeat-containing protein 2, FRCP2

数据库链接:

Organism

基因 ID

SwissProt

背景:

fibronectin type III domain containing 5(FNDC5)encodes 23kDa protein, which is a membrane protein that is cleaved and secreted as a newly identified hormone, irisin. The exercise induces muscle FNDC5 expression. Exercise-induced FNDC5 gene expression in muscles was accompanied by a parallel increase in the concentration of circulating irisin, which in turn activates adipocyte thermogenic programs, leading to mitochondrial heat production and energy expenditure.

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