产品服务
信号通路
说明书下载
货号: TPFL0179
货期: 现货
价格: 1350;2200;3000
所属分类:
靶点: IDO1
应用: WB, IHC, IF/ICC, ELISA
反应性 : human
宿主物种 : Rabbit
MW(CalcμLated) : 403 aa, 45 kDa
MW(Observed): 42 kDa
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
组成 : PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 : Antigen affinity purification
储存 : Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 : 440 ug/ml
克隆性 : Polyclonal
抗原&靶点信息
基因名称 : IDO1
蛋白名称 : indoleamine 2,3-dioxygenase 1
别名 : EC:1.13.11.52, IDO, IDO 1, IDO-1, INDO
背景:
IDO1 is the target for therapy in a range of clinical settings, including cancer, chronic infections, autoimmune and allergic syndromes, and transplantation. Elevated IDO1 expression is a hallmark of major viral infections including HIV, HBV, HCV or influenza and also of major bacteria infections, such as Tb, CAP, listeriosis and sepsis. Pathogens are able to highjack the immunosuppressive effects of IDO1 and make use of them to facilitate their own life cycle. MW of IDO1 is 40-42kd (PMID: 14502282; 17055065).


微信客服