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Phospho-H2AX

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说明书下载
货号: TPFL0147
货期: 现货
价格: 1650;950
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所属分类:


靶点: Phospho-H2A.X (S139)
应用: WB | IHC/IF | ICC/IF
反应性 : H,M,R | H,M,R | H,M,R
宿主物种 : Rabbit
MW(CalcμLated) : 15 kDa
MW(Observed): 15 kDa
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:100-1:500; IHC/IF 1:100-1:500; ICC/IF 1:100-1:500
组成 : PBS containing 0.15% ProClin 300, 100 μg/mL BSA and 50% glycerol.
纯化工艺 : Affinity Purification
储存 : Form: Liquid,Shipping condition: Blue Ice,Short-term storage (1–2 weeks): +4°C,Long-term storage: -20°C,Aliquot information:,Aliquot upon delivery,Storage note: Avoid freeze-thaw cycles.
克隆性 : Polyclonal

抗原&靶点信息

基因名称 : H2AX
蛋白名称 : Histone H2AX
别名 : H2a/x, Histone H2A.X, H2AFX, H2AX, H2A histone family member X, γ-H2AX, p-H2AX, p-h2ax

数据库链接:

Organism

基因 ID

SwissProt

Homo sapiens
背景:

Histone H2A.X belongs to the histone H2A family, which is synthesized in G1 and S phase. It is involved in nucleosomal organization of chromatin together with other histone proteins, and is specially important for recombination between immunoglobulin switch regions. H2A.X becomes phosphorylated on serine 139 (to form gamma-H2AFX or H2AX139ph) in response to DNA double strand breaks (DSBs) generated by exogenous genotoxic agents and by stalled replication forks, which promotes DNA repair and maintains genomic stability. | |

细胞定位 : nucleus

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