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货号: TPFL0137
货期: 现货
价格: 1180.00;1980.00;2800.00
所属分类:
靶点: 8-OHdG (DNA/RNA Damage)
应用: IHC-P, IHC-F, IF
反应性 : Species independent
宿主物种 : Rabbit
MW(CalcμLated) : 0.283 kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : IHC-P 1:100-500; IHC-F 1:100-500; IF 1:100-500
组成 : 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
纯化工艺 : affinity purified by Protein A
储存 : Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
浓度 : 1mg/ml
克隆性 : Polyclonal
抗原&靶点信息
基因名称 : 8-OHdG (DNA/RNA Damage)
蛋白名称 : 8-OHdG (DNA/RNA Damage) Rabbit pAb
别名 : 8-hydroxy-2'-deoxyguanosine; 2'-Deoxy-8-oxoguanosine; 7, 8-Dihydro-8-oxo-2'-deoxyguanosine; 8-Oxo-7, 8-dihydro-2'-deoxyguanosine; 8-Oxo-7, 8-dihydrodeoxyguanosine; 2'-Deoxy-8-oxo-D-guanosine; 8-Oxo-7, 8-dihydro-2μ-deoxyguanosine, 8-Oxo-dG; 2'-Deoxy-8-hydroxyguanosine; ; 8-OHdG;
数据库链接:
Organism
基因 ID
SwissProt
背景:
8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer's disease.


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