信号通路

联系我们

15392937510

地址:湖北省武汉市江夏区神墩四路 666 号武汉国英种业大厦A栋14F 
邮箱:pinuofei2017@163.com
TEL:15392937510

TRIM63 Polyclonal antibody

复制产品信息

说明书下载
货号: TPFL0110
货期: 现货
价格: 1350;2200;3000
+

所属分类:


靶点: TRIM63
应用: WB, IHC, IF/ICC, IF-P, ELISA
反应性 : human, mouse, rat
宿主物种 : Rabbit
MW(CalcμLated) : 40 kDa
MW(Observed): 40-45 kDa
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated

隐藏域元素占位

详细信息

组成 : PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 : Antigen affinity purification
储存 : Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 : 700 ug/ml
克隆性 : Polyclonal

抗原&靶点信息

基因名称 : TRIM63
蛋白名称 : tripartite motif-containing 63
别名 : MuRF1, E3 ubiquitin-protein ligase TRIM63, EC:2.3.2.27, IRF, Iris RING finger protein

数据库链接:

Organism

基因 ID

SwissProt

背景:

TRIM63, also named as IRF, MURF1, RNF28 and SMRZ, is E3 ubiquitin ligase. It is regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. TRIM63 may play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway. It may regulate the organization of myofibrils through TTN in muscle cells. TRIM63 is in muscle-specific expression.

推荐产品

相关文献

留言咨询

留下您想咨询的信息,我们会尽快联系您

提交