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货号: TPFL0104
货期: 现货
价格: 980;4000;6000
所属分类:
靶点: Vinculin
应用: WB, IHC, IF/ICC, IF-P, FC , ELISA
反应性 : human, mouse, rat, canine
宿主物种 : Rabbit
MW(CalcμLated) : 1133 aa, 124 kDa
MW(Observed): 124 kDa
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
组成 : PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
纯化工艺 : Antigen affinity purification
储存 : Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
浓度 : 750 ug/ml
克隆性 : Polyclonal
抗原&靶点信息
基因名称 : Vinculin
蛋白名称 : vinculin
别名 : CMD1W, Metavinculin, MV, MVCL, VCL
背景:
Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament (F-actin)-binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It may also play important roles in cell morphology and locomotion. Vinculin is a 117-kDa, 1,066-amino-acid protein which is ubiquitously expressed. Its splice variant, metavinculin (124 kDa), is muscle-specific.


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