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货号: TPFL0098
货期: 现货
价格: 1200;2200;3100
所属分类:
靶点: Alkaline Phosphatase (ALPL)
应用: WB, IHC-P, ELISA
反应性 : Human, Mouse, Rat
宿主物种 : Rabbit
MW(CalcμLated) : 57kDa
MW(Observed): 80kDa
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:5000 - 1:30000 IHC-P 1:200 - 1:2000 ELISA Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
组成 : Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
纯化工艺 : Affinity purification
储存 : Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS containing 50% glycerol and 0.05% BSA
克隆性 : Monoclonal
克隆号 : ARC0245
抗原&靶点信息
基因名称 : ALPL
蛋白名称 : Alkaline phosphatase, tissue-nonspecific isozyme
别名 : HOPS; HPPA; HPPC; HPPI; HPPO; TNAP; TNALP; APTNAP; TNSALP; AP-TNAP; TNS-ALP; Alkaline Phosphatase (ALPL)
背景:
This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects.


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