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货号: TPFL0267
货期: 现货
价格: 1280;2180;2800
所属分类：
靶点: CD68
应用： WB, IHC-P, IF/ICC, FCM
反应性 ： mouse, rat
宿主物种 ： Rabbit
MW(CalcμLated) ： 37 kDa
同种型-Isotype ： IgG
偶联-Conjugate ： Unconjugated
隐藏域元素占位
详细信息
推荐稀释比 ： Western blot (WB): 1:500-2000; Immunohistochemistry (IHC): 1:50-400; Immunofluorescence (IF): 1:50-400; Flow Cytometry (Fixed): 1:50-200
组成 ： 500 ug/ml antibody with PBS, 0.02% NaN3, 1 mg/ml BSA and 50% glycerol.
纯化工艺 ： Immunogen affinity purified.
储存 ： 12 months from date of receipt，-20℃ as supplied.
浓度 ： 500 ug/ml
克隆性 ： Polyclonal
抗原&靶点信息
基因名称 ： CD68
别名 ： CD68; CD68 molecule; GP110; Macrosialin; SCARD1
背景：
CD68, cluster of differentiation, is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. CD68 is a member of a family of hematopoietic mucin-like molecules that includes leukosialin/CD43 and stem cell antigen CD34. The CD68 gene is mapped to 17p13.1. Immunohistochemistry can be used to identify the presence of CD68, which is found in the cytoplasmic granules of a range of different blood cells. It is particularly useful as a marker for the various cells of the macrophage lineage, including monocytes, histiocytes, giant cells, Kupffer cells, and osteoclasts. This allows it to be used to distinguish diseases of otherwise similar appearance, such as the monocyte/macrophage and lymphoid forms of leukaemia (the latter being CD68 negative). Its presence in macrophages also makes it useful in diagnosing conditions related to proliferation or abnormality of these cells, such as malignant histiocytosis, histiocytic lymphoma, and Gaucher's disease.
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