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货号: TPFL0086
货期: 现货
价格: 1280;2180;2800
所属分类:
靶点: STAT3
应用: WB, IHC-P, IF/ICC, FCM
反应性 : human, mouse, rat
宿主物种 : Rabbit
MW(CalcμLated) : 88 kDa
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
推荐稀释比 : Western blot (WB): 1:500-2000; Immunohistochemistry (IHC): 1:50-200; Immunocytochemistry/Immunofluorescence (ICC/IF): 1:50-200; Flow Cytometry (FCM): 1:50
组成 : 500 ug/ml; Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide, 0.4-0.5 mg/ml BSA and 50% glycerol.
纯化工艺 : Affinity-chromatography
储存 : 12 months from date of receipt,-20℃ as supplied.
浓度 : 500 ug/ml
克隆性 : Monoclonal
抗原&靶点信息
基因名称 : STAT3
别名 : Acute phase response factor; APRF; HIES; STAT3
背景:
The transcription factor, signal transducer and activator of transcription-3 (STAT-3) is the most pleiotropic member of the signal transducer and activator of transcription (STAT) family of transcription factors and mediates pivotal responses for the cytokine family. The mouse STAT3 gene contains 24 exons and spans 30 kb. The translation initiation codon is in exon 2, and the stop codon is in exon 24. STAT3 is mapped to 17q21. It contributes to various physiological processes. Hepatic STAT-3 signaling is thus essential for normal glucose homeostasis and may provide new therapeutic targets for diabetes mellitus.


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