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货号: TPFL0039
货期: 现货
价格: 790;1240;1990;3790
所属分类:
靶点: Tom20
应用: WB, IP, IHC, IF
反应性 : Human, Mouse, Rat, Monkey
宿主物种 : Rabbit
MW(CalcμLated) : 16 kDa
同种型-Isotype : IgG
偶联-Conjugate : Unconjugated
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:1000
组成 : PBS, pH 7.2+50% Glycerol+0.05% BSA+0.01% NaN₃
储存 : –20°C (avoid freeze-thaw cycles), 2 years
克隆性 : Monoclonal
克隆号 : H21N23
抗原&靶点信息
特异性 : TOMM20 Antibody (Rabbit mAb) [H21N23]
基因名称 : TOMM20
蛋白名称 : Mitochondrial import receptor subunit TOM20 homolog
别名 : KIAA0016 | MAS20 | MGC117367 | Mitochondrial 20 kDa outer membrane protein | Mitochondrial import receptor subunit TOM20 homolog | MOM19 | Outer mitochondrial membrane receptor Tom20 | TOM20 | TOMM20 | translocase of outer mitochondrial membrane 20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | translocase of outer mitochondrial membrane 20 homolog type II
背景:
Mitochondria play a crucial role in cellular energy metabolism and are indispensable organelles in eukaryotic cells. Although the human mitochondrial genome encodes 13 proteins, most mitochondrial proteins are synthesized in the cytoplasm as precursors and then transported across mitochondrial membranes through translocase protein complexes. The translocase of the outer mitochondrial membrane (TOM complex) facilitates the import of proteins across this membrane, while the translocase of the inner mitochondrial membrane (TIM complex) facilitates protein transport into the mitochondrial matrix. The TOM complex contains the receptors TOM20, TOM22, TOM70, and the channel-forming protein TOM40. TOM20 is located on the outer mitochondrial membrane and initially recognizes precursors containing presequences, thereby promoting protein import across the membrane. Subsequently, the presequence recognized by TOM20 is connected to the TOM40 protein complex, enabling efficient sequential import of proteins.


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