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货号: TPFL0021
货期: 现货
价格: 2003.49
所属分类:
靶点: Iba1
应用: WB, Flow Cyt (Intra), IHC-Fr, IHC-P, ICC/IF
反应性 : Mouse, Rat, Human
宿主物种 : Rabbit
MW(CalcμLated) : 16 kDa
MW(Observed): 10 kDa; 15 kDa; 17 kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : IHC-Fr: 1/200;WB: 1/500 - 1/2000;ICC/IF: 0.1-1 µg/mL;Flow Cyt (Intra): 1/160;IHC-P: 1/2000
组成 : Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
纯化工艺 : Affinity purification Protein A
储存 : Form: Liquid,Shipping condition: Blue Ice,Short-term storage (1–2 weeks): +4°C,Long-term storage: -20°C,Aliquot information:,Aliquot upon delivery,Storage note: Avoid freeze-thaw cycles.
克隆性 : Monoclonal
克隆号 : EPR16588
抗原&靶点信息
特异性 : <p>For ab178846 Abcam recommends blocking in 3% milk for cleanest results in WB. Blocking with BSA gives slightly higher background.</p><p>Iba1 is a relatively minor protein of brain and is much more abundant in spleen (PMID: 8912632, PMID: 29232670&#41;. We suggest loading higher amount of brain lysate or using lower dilution of antibody for detecting signal in brain related lysates</p>
基因名称 : AIF1
蛋白名称 : Allograft inflammatory factor 1
别名 : G1, IBA1, AIF1, Allograft inflammatory factor 1, AIF-1, Ionized calcium-binding adapter molecule 1, Protein G1, iba1, iba-1, iba 1
背景:
Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.


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