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货号: TPFL0019
货期: 现货
价格: 2063.38
所属分类:
靶点: Myeloperoxidase
应用: WB, IHC-P, ICC/IF, Flow Cyt (Intra)
反应性 : Mouse, Rat, Human
宿主物种 : Rabbit
MW(CalcμLated) : 83 kDa
MW(Observed): 59 kDa; 39 kDa; 89 kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB: 1/1000;ICC/IF: 1/100;Flow Cyt (Intra): 1/500;IHC-P: 1/1000
组成 : pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
纯化工艺 : Affinity purification Protein A
储存 : Form: Liquid,Shipping condition: Blue Ice,Short-term storage (1–2 weeks): +4°C,Long-term storage: -20°C,Aliquot information:,Aliquot upon delivery,Storage note: Avoid freeze-thaw cycles.
克隆性 : Monoclonal
克隆号 : EPR20257
抗原&靶点信息
特异性 : This antibody is specific to Myeloperoxidase heavy chain.
基因名称 : MPO
蛋白名称 : Myeloperoxidase
别名 : Myeloperoxidase, MPO
背景:
Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity (PubMed : 9922160). Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage (PubMed : 25698971).


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