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货号: STA03040
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: SOCS7
应用: WB IHC
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 63kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500~1:2000 IHC 1:50~1:200
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : SOCS7 Antibody detects endogenous levels of total SOCS7
别名 : Ash and phospholipase C gamma-binding protein; NAP4; Nck; Nck Ash and phospholipase C binding protein; Nck associated protein 4; NCKAP4; SH2 domain containing SOCS box protein; SOCS4; SOCS6; Socs7; Suppressor of cytokine signaling 7;
数据库链接:
背景:
Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA.


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