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货号: STA00605
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: Phospho-MSK1
应用: WB IHC ICC/IF IP
反应性 : Human Rat
宿主物种 : Rabbit
MW(Observed): 90kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF1:50~1:200 IP 1:50
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : Phospho-MSK1 (S376) Antibody detects endogenous levels of Phospho-MSK1 (S376)
别名 : 90 kDa ribosomal protein S6 kinase polypeptide 5; EC 2.7.11.1; KS6A5; MSPK1; Nuclear mitogen- and stress-activated protein kinase-1; RLPK; RPS6KA5; kinase MSK1; ribosomal protein S6 kinase;
数据库链接:
背景:
Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin.


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