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货号: STA00555
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: SGK1
应用: WB IHC IP FC
反应性 : Human Mouse Rat
宿主物种 : Rabbit
MW(Observed): 57kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500~1:1000 IHC 1:50~1:200 IP 1:50 FC 1:30
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : SGK1 Antibody detects endogenous levels of SGK1
别名 : EC 2.7.11.1; SGK; SGK1; Serum/glucocorticoid-regulated kinase; Sgk; Sgk1; kinase SGK;
数据库链接:
背景:
Serum and glucocorticoid-inducible kinase (SGK) is a serine/threonine kinase closely related to Akt. SGK is rapidly induced in response to a variety of stimuli, including serum, glucocorticoid, follicle stimulating hormone, osmotic shock, and mineralocorticoids. SGK activation can be accomplished via HGF PI3K-dependent pathways and by integrin-mediated PI3K-independent pathways. Induction and activation of SGK has been implicated in activating the modulation of anti-apoptotic and cell cycle regulation.


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