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货号: STA00544
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: GRK2
应用: WB IHC
反应性 : Human Mouse Rat
宿主物种 : Rabbit
MW(Observed): 80kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500~1:2000 IHC 1:50~1:200
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : GRK2 Antibody detects endogenous levels of GRK2
别名 : GRK2; BARK1; FLJ16718; BETA-ARK1; ADRBK1;
数据库链接:
背景:
GRK2 kinase activity and cellular localization are tightly regulated by interactions with activated receptors, G-beta and G-gamma subunits, adaptor proteins, phospholipids, caveolin and calmodulin, as well as by phosphorylation. PKC phosphorylation enhances GRK2 activity by promoting its membrane localization and by abolishing the inhibitory association of calmodulin.


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