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Fibrillarin Antibody

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说明书下载
货号: STA00454
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
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所属分类:


靶点: Fibrillarin
应用: WB IHC ICC/IF IP FC
反应性 : Human Mouse Rat
宿主物种 : Rabbit
MW(Observed): 33kDa
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500~1:2000 IHC 1:50~1:100 ICC/IF 1:50~1:100 IP : 1:30 FC 1:50
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal

抗原&靶点信息

特异性 : Fibrillarin Antibody detects endogenous levels of total Fibrillarin
别名 : FBL;FIB;FLRN;RNU3IP1;

数据库链接:

Organism

基因 ID

SwissProt

背景:

Fibrillarin is a 2'-O-methyltransferase located in fibrillar regions and Cajal bodies of the nucleolus, where RNA transcription and pre-RNA processing take place. Fibrillarin associates with several other structual proteins as well as box C/D snoRNA to form a complex that functions in pre-rRNA processing, pre-rRNA methylation and ribosome assembly. This complex catalyzes site-specific 2'-O-ribose methylation of targeted nucleotides within the rRNA sequence. The sequence, structure and function of fibrillarin are highly conserved and fibrillarin gene expression is essential for early embryonic development.

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