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货号: STA00426
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: Histone
应用: WB IHC ICC/IF
反应性 : Human Mouse Rat
宿主物种 : Rabbit
MW(Observed): 15kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500~1:2000 IHC 1:500~1:2000 ICC/IF 1:100~1:500
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : Histone H3 (mono methyl K18) Antibody detects endogenous levels of total Histone H3 (mono methyl K18)
别名 : H3 histone; HIST1H3A; Histone cluster 1, H3a; H3K18me1;
数据库链接:
背景:
H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.


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