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货号: STA00252
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: ErbB3
应用: WB IP
反应性 : Human Rat
宿主物种 : Rabbit
MW(Observed): 185kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500~1:2000 IP 1:30
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : ErbB3 (HER3) Antibody detects endogenous levels of total ErbB3 (HER3)
别名 : ERB3, ERBB3, HER3, c-erbB3, kinase ErbB3
数据库链接:
背景:
This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation.


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