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货号: STA00141
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: NAK/TBK1
应用: WB IHC ICC/IF
反应性 : Human Mouse Rat
宿主物种 : Rabbit
MW(Observed): 84kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : NAK/TBK1 (N-term) Antibody detects endogenous levels of total NAK/TBK1 (N-term)
别名 : NAK; T2K; NF-kappa-B-activating kinase; TANK-binding kinase 1; Serine/threonine-protein kinase TBK1; T2K; TANK binding kinase 1;
数据库链接:
背景:
The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex.


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