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CD3 (ABT295) mouse mAb

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说明书下载
货号: PH0174
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+


靶点: CD3E
应用: IHC,ELISA
反应性 : Human,
宿主物种 : Mouse
MW(CalcμLated) : 23kD
MW(Observed): 23kD
同种型-Isotype : IgG2a,Kappa

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:50-200;ELISA 1:500-5000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : ABT295

抗原&靶点信息

特异性 : The antibody can specifically recognize human CD3e protein, and shows no reaction with CD3d or CD3g.
基因名称 : CD3E T3E
蛋白名称 : CD3, CD3E
别名 : T-cell surface glycoprotein CD3 epsilon chain;T-cell surface antigen T3/Leu-4 epsilon chain;CD antigen CD3e;

数据库链接:

Organism

基因 ID

SwissProt

背景:

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008],

细胞定位 : Membranous

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