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货号: PH0278
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
靶点: Humanm Placental lactogen
应用: IHC,IF,ELISA
反应性 : Human,
宿主物种 : Mouse
MW(Observed): 25kD
同种型-Isotype : IgG2b,Kappa
隐藏域元素占位
详细信息
推荐稀释比 : IHC 1:200-400;IF 1:50-200;ELISA 1:500-5000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : ABT223
抗原&靶点信息
特异性 : This antibody detects endogenous levels of hPL.
基因名称 : CSH1/CSH2
蛋白名称 : Chorionic somatomammotropin hormone 1/Chorionic somatomammotropin hormone 2
别名 : PL;CSB;CS-2;GHB1;hCS-B;CSA;CS-1;CSMT;GHB3;hCS-1;hCS-A
数据库链接:
背景:
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq, Jul 2008]


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