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货号: PF0497
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: PNK1
应用: WB,IHC
反应性 : Human,Rat,Mouse,
宿主物种 : Rabbit
MW(Observed): 57kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
修饰-Modification : Phospho
推荐稀释比 : WB 1:500-2000;IHC 1:50-300
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : This antibody detects endogenous levels of Human PNK1 (phospho-Ser114 or Thr118)
基因名称 : PNKP
蛋白名称 : PNK1 (Ser114/Thr118)
别名 : Bifunctional polynucleotide phosphatase/kinase;DNA 5'-kinase/3'-phosphatase;Polynucleotide kinase-3'-phosphatase;[Includes: Polynucleotide 3'-phosphatase;2';3';-polynucleotidase;Polynucleotide 5'-hydroxyl-kinase;]
背景:
This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay.[provided by RefSeq, Sep 2010],


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