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ERCC2 Polyclonal Antibody

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说明书下载
货号: PG8386
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: ERCC2
应用: WB,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 83kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;ELISA 1:5000-20000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : ERCC2 Polyclonal Antibody detects endogenous levels of protein.
基因名称 : ERCC2 XPD XPDC
蛋白名称 : TFIIH basal transcription factor complex helicase XPD subunit (Basic transcription factor 2 80 kDa subunit) (BTF2 p80) (CXPD) (DNA excision repair protein ERCC-2) (DNA repair protein complementing XP-D cells) (TFIIH basal transcription factor complex 80 kDa subunit) (TFIIH 80 kDa subunit) (TFIIH p80) (Xeroderma pigmentosum group D-complementing protein)

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],

细胞定位 : Nucleus . Cytoplasm, cytoskeleton, spindle .

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