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SAP18 rabbit pAb

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说明书下载
货号: PD0663
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: SAP18
应用: WB,IHC
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(CalcμLated) : 17kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;IHC 1:50-300
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of SAP18 at Human/Mouse
基因名称 : SAP18 GIG38
蛋白名称 : SAP18

数据库链接:

Organism

基因 ID

SwissProt

背景:

Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2008],

细胞定位 : Nucleus . Cytoplasm . Nucleus speckle . Shuttles between the nucleus and the cytoplasm (PubMed:16314458). Colocalizes with ACIN1 and SRSF2 in nuclear speckles (PubMed:20966198). .

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