产品服务
信号通路
详细信息
推荐稀释比 ： WB 1:1000;ICC 1:400;IP 1:100;IF 1:50-200
组成 ： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 ： The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
储存 ： -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 ： Monoclonal
抗原&靶点信息
特异性 ： This antibody detects endogenous levels of Ku80 and does not cross-react with related proteins.
基因名称 ： xrcc5
别名 ： ATP dependent DNA helicase II 80 kDa subunit;ATP dependent DNA helicase II 86 Kd subunit;ATP dependent DNA helicase II;ATP-dependent DNA helicase 2 subunit 2;ATP-dependent DNA helicase II 80 kDa subunit;CTC box binding factor 85 kDa;CTC box-binding factor 85 kDa subunit;CTC85;CTCBF;DNA repair protein XRCC5;Double strand break rejoining;FLJ39089;G22P2;KARP 1;KARP1;Ku 80;Ku autoantigen 80kDa;Ku80;Ku86;Ku86 autoantigen related protein 1;KUB 2;KUB2;Lupus Ku autoantigen protein p86;NFIV;Nuclear factor IV;Thyroid lupus autoantigen;Thyroid-lupus autoantigen;TLAA;X ray repair complementing defective repair in Chinese hamster cells 5;double strand break rejoining;X-ray repair complementing defective repair in Chinese hamster cells 5;double-strand-break rejoining;X-ray repair cross-complementing protein 5;Xray repair complementing defective repair in Chinese hamster cells 5;XRCC 5;XRCC5;XRCC5_HUMAN.
背景：
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008],
细胞定位 ： Nucleus . Nucleus, nucleolus . Chromosome .
推荐产品
相关文献
我们始终开放沟通，期待为您提供支持。
我们以一抗、二抗产品为核心，深耕抗体试剂细分领域。依托自主搭建的核心技术平台与专业的研发生产团队，我们为全球高校、科研院所、生物医药企业等客户提供高可靠性的生物试剂产品及全链条技术
支持服务。自成立以来，Pinofibio 始终坚守“以科研需求为导向”的发展理念，通过完善的研发体系、严苛的质量控制与高效的服务响应，致力于构建覆盖多物种、多靶点的抗体产品矩阵，助力科研工作者攻克技术难题，推动生物医药产业的创新发展。
武汉市皮诺飞生物科技有限公司
地址：湖北省武汉市江夏区神墩四路 666 号武汉国英种业大厦A栋14F
邮箱：pinuofei2017@163.com
TEL：15392937510
小红书
实验服务
公众号
抗体服务
微信客服