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FAN1 rabbit pAb

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说明书下载
货号: PD0452
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
+

所属分类:


靶点: FAN1
应用: WB
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(CalcμLated) : 112kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : This antibody detects endogenous levels of FAN1 at Human/Mouse
基因名称 : FAN1 KIAA1018 MTMR15
蛋白名称 : FAN1

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene plays a role in DNA interstrand cross-link repair and encodes a protein with 5' flap endonuclease and 5'-3' exonuclease activity. Mutations in this gene cause karyomegalic interstitial nephritis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Feb 2016],

细胞定位 : Nucleus . Localizes at sites of DNA damage following recruitment by monoubiquitinated FANCD2 (PubMed:20603015, PubMed:20603016). Localizes to stalled replication forks via its UBZ4-type zinc finger (PubMed:20935496). .

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