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XRN1 Polyclonal Antibody

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说明书下载
货号: PG7056
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: XRN1
应用: WB,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 187kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;ELISA 1:5000-20000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : XRN1 Polyclonal Antibody detects endogenous levels of protein.
基因名称 : XRN1 SEP1
蛋白名称 : 5'-3' exoribonuclease 1 (Strand-exchange protein 1 homolog)

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],

细胞定位 : Cytoplasm . Discrete foci at the inner surface of the cell membrane.

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